Re: Burning and Aching Vaginal Area
Oh my. I don't quite understand why you think estradiol isn't natural. Estradiol is the primary estrogen produced by your ovaries from puberty until menopause, and is a profoundly powerful hormone. It's the reason you developed breasts etc at puberty. It reaches extremely high levels at pregnancy to aid in baby development and delivery. Estriol is indeed a "natural" estrogen, but it is made by the placenta. If you aren't pregnant, you don't have estriol, and you don't particularly need it. It is a very weak estrogen, without the proven benefits of estradiol.
What you need to try is Vagifem. It delivers a small dose of estradiol right into the vagina, and get soaked up right in that area. My mother was going to the bathroom 6 or 7 times a night and had the burning sensation you describe in your pelvic area. After using the Vagifem every day for a week, and then twice a week or so, she stopped feeling like she needed to urinate constantly, and the pain stopped. It took a few months for the pain to completely go away, but that's because it takes nerves a long time to recover.
A lot of women have problems with an estradiol cream, particularly an Estrace cream , because it has polyethylene glycol in it, which often burns sensitive vaginal tissues. Vagifem has a slower release and seems to work better for that reason.
Because the dose is low, and it does not affect the body on a system wide basis, like oral estrogens, this therapy is not thought to have any of the dangers of an increase in endometrial cancer or stroke (stroke risk is increased with oral estrogens). Still, watch out for any spotting or bleeding, and have it checked out with your doctor. Once the problem is fixed, you may find that you need very little to keep the area healthy. I would also strongly recommend that you go to the library, check out a book called Screaming To Be Heard, by Elizabeth Lee Vliet, MD, and look at pages 310-337, for a lot more information. Good luck!