His and Her Health

Have you had any experience with topical compounded amitriptyline or tricyclics/ other drugs that might be effective in alleviating some types of vulvar pain associated with vestibulodynia? I have been diagnosed with both vestibulodynia and PFD but have found limited relief after 3 months of PF PT.

Here is a link to one of Dr. Goldstein's articles that may give you some answers.

http://www.cvvd.org/vulvar_vestibulitis

RMC

Did you see a pt in DC? am in Hagerstown and was looking for a good pt but am also not having success with the pts I have seen.
Is your pt located right in DC or in MD?

thanks!

I have read Dr. Goldstein's articles but I have also been reading that people who may not have completely responded to tricyclics are having more success with compounded topical versions.

My PT is located in Ashburn, VA--she has said that it could take 4-6 months to really accomplish pelvic floor re-training so I'm trying to stay patient! I can give you more information offline if that would be helpful.

yes thanks I will email you

There have been published reports of using topical Neurontin (which is an anti-epileptic- not TCA).

I think that TCA and other medication have limited use as I think that vestibulodynia is only secondary to neuronal issues in a minority of women.

<small>[ 03-26-2009, 10:41 AM: Message edited by: Moderator ]</small>

Dr Goldstein,
Can you elaborate on what you mean by that statement

Do you mean that pfd causes nerve compression therefore causing vestibulodynia? or do you mean that its neural proliferation and vestibulodynia/pfd is secondary?