It is so easy to say that hormone replacement is bad because clinical trials show us they are bad.
In fact, that is not what clinical trials are showing us. What they are showing us is that hypogonadism (peri-menopause) and profound hypogonadism (menopause) in women are not being taken seriously.
Clinical trials like the Women’s Health Initiative (WHI) were said to use hormone replacement therapy (HRT). The point of any clinical trial that uses HRT is to show that its regimen is replacement and what effect it has. The WHI concluded that profound hypogonadism is untreatable with HRT and that HRT is dangerous and should be avoided.
The conclusions of the WHI are absurd. They are absurd for the following reasons:
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- <font size="2" face="Verdana, Arial">The WHI did not use HRT for the multiple hormone deficiencies of profound hypogonadism. For example, all oral estrogens are also anti-androgens so the profound hypogonadism is immediately made worse.</font></li>
- <font size="2" face="Verdana, Arial">There are no existing drug studies that support the claims that Premarin and Provera replaces any of the 5 best known ovarian hormones.</font></li>
- <font size="2" face="Verdana, Arial">No hormone testing was done during the WHI, so no proof of hormone replacement was given. Which means the trial didn’t do what it was supposed to do.</font></li>
<font size="2" face="Verdana, Arial"> The whole point of HRT trials is to prove replacement is being done and to monitor the health benefits of replacement. In two ways the WHI, a ½ billion dollar ‘HRT’ clinical trial, went to great lengths to provide no proof of replacement. First, by using drugs that cannot support their claims of replacement and second, by actively avoiding the point of the trial, hormone testing to show even partial replacement.
The conclusion of the WHI is irrelevant to the treatment of profound hypogonadism with hormone replacement.
The use of hormone replacement for hormone deficiencies is one of the most successful areas of medicine. That is far more relevant than what the WHI has to say.
Treatment of profound hypogonadism would mean that virtually no one would have osteoporosis, women would continue to have sexual response and wouldn’t need vaginal lubricants as they would naturally produce their own, and they would be healthy enough to maintain their competitiveness in their jobs and the job market.
Hypogonadism and profound hypogonadism are treatable. Don’t let anyone tell you otherwise.